SCHEMBL11207294

SCHEMBL11207294

OCC(Br)C(Br)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MCHR1 Q99705 1/20 0.33
ALOX15 P16050 4/20 0.33
ALOX12 P18054 4/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRA2 P47869 1/20 0.30
GABRB2 P47870 1/20 0.30
AKR1B1 P15121 1/20 0.30
LMNA P02545 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11171954 0.74 HSD17B10 (0.36) TSHRCYP3A4TDP1HSD17B10ALOX15
SCHEMBL11207293 0.72 TSHR (0.36) TSHRCYP3A4TDP1HSD17B10ALOX15
SCHEMBL6285002 0.67 HSD17B10 (0.41) TSHRCYP3A4TDP1HSD17B10ALOX15
SCHEMBL2883398 0.67 ALDH1A1 (0.44) TSHRCYP3A4TDP1HSD17B10ALOX15
SCHEMBL10192340 0.67 ALDH1A1 (0.44) TSHRCYP3A4TDP1HSD17B10ALOX15
SCHEMBL681064 0.67 HSD17B10 (0.38) TSHRCYP3A4TDP1HSD17B10ALOX15
SCHEMBL1537774 0.66 HSD17B10 (0.39) TSHRCYP3A4TDP1HSD17B10ALOX15
SCHEMBL765589 0.66 ALOX12 (0.47) TSHRCYP3A4TDP1HSD17B10ALOX15
SCHEMBL10711308 0.65 TSHR (0.54) TSHRALOX15MEN1KMT2ALMNA
SCHEMBL11206740 0.64 HSD17B10 (0.39) TSHRCYP3A4TDP1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026310-B1 FIRE PROTECTION FINISH FOR RESOL-TYPE RESINOUS LAMINATES Chemische Fabrik Kalk GmbH (DE) 1983-07-27 EP disclosed