Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP5 | P51878 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686594 | 0.77 | HTT (0.52) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL9684556 | 0.76 | LMNA (0.51) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL9298962 | 0.73 | HTT (0.64) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL9685414 | 0.73 | DRD2 (0.49) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL8808175 | 0.72 | HTT (0.65) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL18256926 | 0.72 | DRD4 (0.52) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL10824274 | 0.72 | NPC1 (0.48) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL2800999 | 0.71 | NPC1 (0.51) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL8811787 | 0.71 | LMNA (0.55) | LMNAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL8808001 | 0.71 | HTT (0.67) | LMNAHTTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61076488-A | — | — | None | — | — | JP | disclosed |
| JP-S6176488-A | PYRIDOPYRIMIDINE DERIVATIVE | MITSUI PETROCHEM IND LTD | 1986-04-18 | — | — | JP | disclosed |