Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211866 | 0.84 | HSD11B1 (0.55) | KMT2AKDM4ERAB9AL3MBTL1TDP1 | |
| SCHEMBL493114 | 0.78 | KMT2A (0.75) | KMT2AKDM4ERAB9ANPC1NR1H3 | |
| SCHEMBL4519653 | 0.75 | KMT2A (0.50) | KMT2AKDM4ERAB9AL3MBTL1TDP1 | |
| SCHEMBL2220361 | 0.75 | ALDH1A1 (0.55) | KMT2AKDM4ERAB9AHSD11B1HPGD | |
| SCHEMBL30062 | 0.75 | ALDH1A1 (0.58) | KMT2AKDM4ERAB9ATDP1SMN1; SMN2 | |
| SCHEMBL4039494 | 0.75 | ALDH1A1 (0.58) | KMT2AKDM4ERAB9ATDP1SMN1; SMN2 | |
| SCHEMBL9001653 | 0.74 | KMT2A (0.75) | KMT2AKDM4ERAB9AHPGDNPC1 | |
| SCHEMBL9001651 | 0.74 | KMT2A (0.69) | KMT2AKDM4ERAB9AHPGDNPC1 | |
| SCHEMBL27612994 | 0.73 | TSHR (0.47) | KMT2AKDM4ERAB9AHSD11B1HPGD | |
| SCHEMBL9001629 | 0.73 | KMT2A (0.62) | KMT2AKDM4EL3MBTL1NR1H3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61126062-A | — | — | None | — | — | JP | disclosed |
| JP-S61126062-A | BENZOYLHYDRAZINE DERIVATIVE AND ITS PREPARATION | NIPPON SODA CO LTD | 1986-06-13 | — | — | JP | disclosed |