Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10826321 | 0.97 | MMP1 (0.49) | MMP1MMP3MMEMMP2MMP7 | |
| SCHEMBL10826350 | 0.92 | MME (0.49) | MMEACECPA1ACE2 | |
| SCHEMBL10826528 | 0.89 | MME (0.52) | MMEACE | |
| SCHEMBL7287864 | 0.85 | MMP3 (0.44) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL7287870 | 0.85 | MMP3 (0.44) | MMP1MMP3MMP9MMP2MMP7 | |
| SCHEMBL10826470 | 0.84 | ACE (0.49) | MMEACECPA1ACE2 | |
| SCHEMBL10521239 | 0.84 | HRH4 (0.48) | MMP1MMP3MMP9MMEMMP2 | |
| SCHEMBL10519808 | 0.83 | CAPN1 (0.52) | MMP1MMP3MMP9MMEMMP2 | |
| SCHEMBL9727512 | 0.82 | MME (0.47) | MMP9MMEMMP2MMP7 | |
| SCHEMBL7287009 | 0.82 | MMP2 (0.44) | MMP1MMP3MMP9MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609641-A | HYPOTENSIVE, ANTIALDOSTERONE | MERCK & CO., INC. (US) | 1986-09-02 | — | — | US | disclosed |