SCHEMBL108266

SCHEMBL108266

Nc1ccc(Nc2ccccc2)c([N+](=O)[O-])c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.68
MAPT P10636 6/20 0.67
TDP1 Q9NUW8 6/20 0.67
POLB P06746 2/20 0.67
MEN1 O00255 5/20 0.66
KMT2A Q03164 5/20 0.66
MAPK1 P28482 4/20 0.66
ALDH1A1 P00352 6/20 0.65
CASP7 P55210 1/20 0.65
HCAR3 P49019 1/20 0.64
GFER P55789 1/20 0.59
WNK1 Q9H4A3 1/20 0.58
GAA P10253 3/20 0.56
ALOX15 P16050 3/20 0.56
HTT P42858 1/20 0.56
CYP3A4 P08684 2/20 0.51
RECQL P46063 2/20 0.51
KDM4E B2RXH2 1/20 0.51
NSD2 O96028 1/20 0.51
APEX1 P27695 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31026210 1.00 L3MBTL1 (0.68) L3MBTL1MAPTTDP1POLBMEN1
Hydrochloric Acid SCHEMBL11782928 0.98 L3MBTL1 (0.66) L3MBTL1MAPTTDP1POLBMEN1
SCHEMBL9728612 0.90 MAPT (0.79) L3MBTL1MAPTTDP1POLBMEN1
SCHEMBL293916 0.82 MAPT (0.72) L3MBTL1MAPTTDP1POLBMEN1
SCHEMBL11209685 0.81 MAPT (0.67) L3MBTL1MAPTTDP1POLBMEN1
SCHEMBL9943157 0.81 L3MBTL1 (0.70) L3MBTL1MAPTTDP1POLBMEN1
SCHEMBL1337893 0.81 L3MBTL1 (0.68) L3MBTL1MAPTTDP1POLBMEN1
SCHEMBL337857 0.81 L3MBTL1 (0.68) L3MBTL1MAPTTDP1POLBMEN1
SCHEMBL5159865 0.81 L3MBTL1 (0.68) L3MBTL1MAPTTDP1POLBMEN1
SCHEMBL4938163 0.81 L3MBTL1 (0.68) L3MBTL1MAPTTDP1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 958 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118419934-B Red fluorescent silicon nanoparticle probe for detecting pH, and preparation method and application thereof 浙江大学杭州国际科创中心 2024-11-22 CN claimed
CN-118419934-A Red fluorescent silicon nanoparticle probe for detecting pH, and preparation method and application thereof 浙江大学杭州国际科创中心 2024-08-02 CN claimed
CN-118389366-A Microbial degradation microbial agent for kitchen waste and preparation method thereof 北京中佳元能环保科技有限公司 2024-07-26 CN claimed
CN-117801812-A Red fluorescent silicon nano-dot, preparation method and application thereof 中国科学院苏州生物医学工程技术研究所 2024-04-02 CN claimed
WO-2023171931-A1 HAIR COLORING SHAMPOO COMPOSITION (주)아모레퍼시픽 2023-09-14 WO claimed
CN-114196400-B Preparation method and application of fluorescent carbon dot and film dropping liquid for detecting phosgene in colorimetric and ratio modes 郑州大学 2023-05-23 CN claimed
CN-113322251-B Composite microbial degradation microbial inoculum for kitchen waste treatment and preparation method and application thereof 杭州楠大环保科技有限公司 2022-05-10 CN claimed
CN-114196400-A Preparation method and application of fluorescent carbon dot and membrane dropping liquid for colorimetric and ratiometric detection of phosgene 郑州大学 2022-03-18 CN claimed
US-7799092-B2 Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer L'OREAL S.A. (FR) 2010-09-21 US claimed
US-7736395-B2 direct dyes L'OREAL S.A. (FR) 2010-06-15 US claimed
EP-0646109-B1 NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES OREAL (FR) 1997-09-03 EP claimed
EP-0673926-B1 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres OREAL (FR) 1997-04-09 EP claimed
US-5516942-A DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE L'OREAL (FR) 1996-05-14 US claimed
EP-0673926-A1 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres L'OREAL (FR) 1995-09-27 EP claimed
EP-0646109-A1 NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES. OREAL (FR) 1995-04-05 EP claimed
EP-0646108-A1 HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES L'OREAL (FR) 1995-04-05 EP claimed
WO-1994000415-A1 NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES L'OREAL (FR) 1994-01-06 WO claimed
WO-1994000414-A1 HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES L'OREAL (FR) 1994-01-06 WO claimed
US-3959377-A FROM 4-FLUORO-3-NITROANILINE AND ANILINE CLAIROL INCORPORATED (US) 1976-05-25 US claimed
US-3930792-A NITROAMINOBENZENE, QUATERNARY AMINE, N-OXYALKYLATED FATTY ACID AMIDES CLAIROL INCORPORATED (US) 1976-01-06 US claimed