Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829128 | 0.95 | LTA4H (0.57) | LTA4HSMN1; SMN2LMNAMAPK1NPSR1 | |
| SCHEMBL3446997 | 0.95 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAMAPK1NPSR1DRD2 | |
| SCHEMBL17164056 | 0.90 | DRD2 (0.57) | LTA4HSMN1; SMN2LMNAMAPK1NPSR1 | |
| SCHEMBL2353375 | 0.87 | MTNR1A (0.65) | LTA4HSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL9634003 | 0.84 | MTNR1A (0.53) | LTA4HSMN1; SMN2LMNAMAPK1DRD2 | |
| SCHEMBL9632354 | 0.84 | MAPT (0.51) | LTA4HSMN1; SMN2LMNAMAPK1DRD2 | |
| Cyclopropane SCHEMBL9509777 | 0.83 | RAB9A (0.61) | LTA4HSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL9161433 | 0.82 | PPARA (0.60) | SMN1; SMN2RAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL10828184 | 0.82 | L3MBTL1 (0.66) | LTA4HSMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL10828131 | 0.82 | FFAR4 (0.56) | LTA4HLMNARAB9AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114968-A | Ovicides, pesticides | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0395578-A2 | Acylated carbamic acid esters | CIBA-GEIGY AG (CH) | 1990-10-31 | — | — | EP | disclosed |