Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827670 | 0.91 | PARG (0.44) | TDP1POLBPARGHDAC6ACSS2 | |
| SCHEMBL10827126 | 0.85 | TSHR (0.41) | TDP1POLBKDM4ETSHRL3MBTL1 | |
| SCHEMBL10827387 | 0.84 | ALDH1A1 (0.44) | KDM4ETSHRCA12CA1CA2 | |
| SCHEMBL10827069 | 0.82 | CYP3A4 (0.46) | TDP1KDM4EALOX15TSHRL3MBTL1 | |
| SCHEMBL10827674 | 0.79 | PDE10A (0.41) | TDP1POLBHDAC6KDM4EL3MBTL1 | |
| SCHEMBL10828444 | 0.76 | TSHR (0.41) | TDP1POLBPARGKDM4ETSHR | |
| SCHEMBL10827391 | 0.76 | ALDH1A1 (0.43) | HDAC6HDAC8KDM4ETSHR | |
| SCHEMBL10827385 | 0.75 | KDM4E (0.44) | TDP1POLBKDM4EALOX15TSHR | |
| SCHEMBL10827144 | 0.73 | ALDH1A1 (0.42) | PARGPTGS2ALOX15TSHRL3MBTL1 | |
| SCHEMBL3821330 | 0.71 | PARG (0.50) | TDP1PARGHDAC6ACSS2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605657-A | 4-quinazalone fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-08-12 | — | — | US | disclosed |