Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827387 | 0.93 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL10827670 | 0.84 | PARG (0.44) | KDM4ETSHRHDAC8HDAC6PDE5A | |
| SCHEMBL10827144 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10827110 | 0.80 | KLK7 (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL10828444 | 0.79 | TSHR (0.41) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL10827380 | 0.77 | PDE10A (0.48) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL10828363 | 0.76 | TDP1 (0.36) | KDM4ETSHRHDAC8HDAC6 | |
| SCHEMBL10827393 | 0.74 | LMNA (0.49) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL24090141 | 0.72 | USP2 (0.43) | ALDH1A1MAPTKDM4EHPGDHTT | |
| SCHEMBL10827145 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605657-A | 4-quinazalone fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-08-12 | — | — | US | disclosed |