Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827107 | 0.91 | DDR1 (0.38) | PDE10APOLBTDP1KDM4EMEN1 | |
| SCHEMBL10827676 | 0.85 | RORA (0.45) | PDE10AKCNH2HRH3POLBTDP1 | |
| SCHEMBL10827393 | 0.82 | LMNA (0.49) | CTSDKCNH2HRH3KDM4EMEN1 | |
| SCHEMBL10827069 | 0.82 | CYP3A4 (0.46) | PDE10ATDP1KDM4EMEN1KMT2A | |
| SCHEMBL10827062 | 0.80 | CTSD (0.45) | PDE10ACTSDKCNH2HRH3KDM4E | |
| SCHEMBL10828363 | 0.79 | TDP1 (0.36) | POLBTDP1KDM4EL3MBTL1HDAC6 | |
| SCHEMBL10827322 | 0.76 | RORA (0.45) | POLBTDP1KDM4ECTSKALDH1A1 | |
| SCHEMBL10827385 | 0.75 | KDM4E (0.44) | PDE10APOLBTDP1KDM4EMEN1 | |
| SCHEMBL10827110 | 0.74 | KLK7 (0.48) | KDM4EMEN1KMT2ACTSKALDH1A1 | |
| SCHEMBL10827670 | 0.72 | PARG (0.44) | POLBTDP1KDM4EL3MBTL1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605657-A | 4-quinazalone fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-08-12 | — | — | US | disclosed |