Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827126 | 0.92 | TSHR (0.41) | TSHRPTK2BTDP1ALDH1A1KDM4E | |
| SCHEMBL10827670 | 0.85 | PARG (0.44) | TSHRTDP1KDM4EPOLBL3MBTL1 | |
| SCHEMBL10827671 | 0.84 | DPP4 (0.43) | TSHRPTK2BTDP1ALDH1A1GAA | |
| SCHEMBL10827322 | 0.82 | RORA (0.45) | TSHRPTK2BTDP1ALDH1A1KDM4E | |
| SCHEMBL10827391 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL10828440 | 0.78 | NPSR1 (0.45) | TSHRPTK2BTDP1ALDH1A1KDM4E | |
| SCHEMBL10828363 | 0.76 | TDP1 (0.36) | TSHRTDP1KDM4EPOLBL3MBTL1 | |
| SCHEMBL10827144 | 0.76 | ALDH1A1 (0.42) | TSHRALDH1A1GAAMAPTMEN1 | |
| SCHEMBL10827676 | 0.76 | RORA (0.45) | TSHRPTK2BTDP1ALDH1A1KDM4E | |
| SCHEMBL10827387 | 0.72 | ALDH1A1 (0.44) | TSHRALDH1A1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605657-A | 4-quinazalone fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-08-12 | — | — | US | disclosed |