Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830235 | 0.81 | TSHR (0.59) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10830241 | 0.80 | ADORA3 (0.37) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10950737 | 0.76 | ALDH1A1 (0.52) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10830287 | 0.72 | HSD17B10 (0.44) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7245896 | 0.72 | ADORA3 (0.57) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4118573 | 0.71 | ALDH1A1 (0.41) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7434340 | 0.67 | ADORA3 (0.62) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7951620 | 0.66 | CACNA1C (0.71) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28735975 | 0.66 | TSHR (0.56) | ADORA3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10675403 | 0.66 | KDM4E (0.69) | ADORA3MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567268-A | Process for preparation of certain tetrahydrofuro[3,4-b]pyridines | MERCK & CO., INC. (US) | 1986-01-28 | — | — | US | disclosed |