Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.55 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368245 | 0.85 | LMNA (0.46) | GABRA1GABRB2MMP2CYP1A2CYP3A4 | |
| SCHEMBL2894057 | 0.84 | MMP2 (0.41) | GABRA1GABRB2MMP2CYP1A2CYP3A4 | |
| SCHEMBL2897266 | 0.77 | LMNA (0.46) | GABRA1GABRB2MMP2CYP1A2CYP3A4 | |
| SCHEMBL2902418 | 0.75 | PIN1 (0.50) | MMP2MMP1MMP9MAPK1C3AR1 | |
| Azietomidate SCHEMBL1044050 | 0.71 | GABRA1 (1.00) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| Sulfuric Acid SCHEMBL11728620 | 0.70 | PIN1 (0.44) | MMP2LMNAMMP1MMP9C3AR1 | |
| SCHEMBL2894225 | 0.66 | MMP2 (0.44) | MMP2LMNAMAPK1 | |
| SCHEMBL15964599 | 0.64 | CYP1A2 (0.47) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL19207667 | 0.63 | MMP2 (0.59) | GABRA1GABRB2MMP2CYP1A2CYP3A4 | |
| SCHEMBL1083035 | 0.62 | GABRA1 (0.43) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005969-A2 | ETOMIDATE ANALOGUES THAT DO NOT INHIBIT ADRENOCORTICAL STEROID SYNTHESIS | THE GENERAL HOSPITAL CORPORATION (US) | 2011-01-13 | — | — | WO | disclosed |