SCHEMBL1083090

SCHEMBL1083090

CO[SiH](C=Cc1ccccc1)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.48
MAOB P27338 1/20 0.44
NFE2L2 Q16236 2/20 0.44
TUBB1 Q9H4B7 2/20 0.42
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42
TUBA3E Q6PEY2 1/20 0.42
TUBA1A Q71U36 1/20 0.42
TUBA1C Q9BQE3 1/20 0.42
TUBB6 Q9BUF5 1/20 0.42
TUBB2B Q9BVA1 1/20 0.42
CYP1A1 P04798 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11259781 0.81 SIGMAR1 (0.44) TRPA1KDM4EMEN1ALDH1A1TP53
SCHEMBL10499123 0.80 TRPA1 (0.52) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL8760080 0.80 RELA (0.52) MAOBNFE2L2TUBB1TUBB4ATUBB
SCHEMBL2502119 0.77 TRPA1 (0.39) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL73089 0.77 RELA (0.48) TRPA1MAOBCYP1A2CHATKDM4E
SCHEMBL30923503 0.77 TRPA1 (0.44) TRPA1MAOBNFE2L2CHATKDM4E
SCHEMBL886959 0.75 RELA (0.43) TRPA1MAOBNFE2L2TUBB1TUBB4A
(Z)-1,2-Diphenylethene SCHEMBL28053570 0.75 TRPA1 (0.68) TRPA1MAOBNFE2L2TUBB1TUBB4A
SCHEMBL15661092 0.74 GLA (0.50) MAOBCYP1A2CYP1B1MEN1ALDH1A1
SCHEMBL3626138 0.74 RELA (0.42) TRPA1MAOBCYP1A2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118755031-A Sulfonate grafted organic silicon flame retardant, and preparation method and application thereof 熵能创新材料(珠海)有限公司 2024-10-11 CN claimed
CN-115894935-A Phosphorus-containing vinyl polysiloxane and preparation method and application thereof 江南大学 2023-04-04 CN claimed
CN-113322039-B Single-component silane modified polyether heat conduction material and preparation method thereof 烟台德邦科技股份有限公司 2023-02-03 CN claimed
CN-115505239-A Preparation method of polysiloxane modified epoxy resin material 山东大学 2022-12-23 CN claimed
CN-112126067-B Preparation method and application of liquid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2022-04-05 CN claimed
CN-112126064-B Preparation method of solid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2022-04-05 CN claimed
CN-110128657-B Synthesis of isotactic structure polyvinyl polysiloxane and method for preparing high tear-resistant silicone rubber 中国航发北京航空材料研究院 2022-03-15 CN claimed
CN-112094414-B Preparation method of novel liquid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2022-01-07 CN claimed
CN-113322039-A Single-component silane modified polyether heat conduction material and preparation method thereof 烟台德邦科技股份有限公司 2021-08-31 CN claimed
CN-110003842-B Single-component dealcoholized room temperature vulcanized organopolysiloxane composition 烟台德邦科技股份有限公司 2021-05-04 CN claimed
CN-112126065-A Preparation method of solid silicon carbide ceramic precursor 长沙科航特种织造有限公司 2020-12-25 CN claimed
CN-112126067-A Preparation method and application of novel liquid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2020-12-25 CN claimed
CN-112126064-A Preparation method of novel solid silicon carbide ceramic precursor 长沙科航特种织造有限公司 2020-12-25 CN claimed
CN-111925386-B Preparation method of novel silicon carbide ceramic precursor 长沙科航特种织造有限公司 2020-12-22 CN claimed
CN-112094414-A Preparation method of novel liquid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2020-12-18 CN claimed
US-20200388876-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH SILICON CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US claimed
CN-111925386-A Preparation method of novel silicon carbide ceramic precursor 长沙科航特种织造有限公司 2020-11-13 CN claimed
CN-111732730-A High-temperature-resistant borosilicate rubber raw rubber and synthetic method thereof 北京宇航系统工程研究所 2020-10-02 CN claimed
US-5021091-A Aluminum perchlorate curing catalyst; improved shelf stability SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-06-04 US claimed
US-4889904-A HEATING MIXTURE OF ALKOXY-FUNCTIONAL DISILANE AND EITHER ALKOXY-FUNCTIONAL SILANE WITH UNSATURATED SUBSTITUENT OR UNSATURATED HYDROCARBON DOW CORNING CORPORATION (US) 1989-12-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200388876-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH SILICON CONTAINING ELECTROLYTE ADDITIVES SELENOI, SIK1, SIK2 TRPA1 590/4885MAOB 4042/4885NFE2L2 1172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.