Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AMPD1 | P23109 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114461 | 0.98 | TLR8 (0.39) | TLR8HSD11B1ALDH1A1TBXAS1AMPD1 | |
| SCHEMBL5274280 | 0.91 | ALDH1A1 (0.39) | TLR8HSD11B1ALDH1A1KMT2APOLB | |
| SCHEMBL5278999 | 0.87 | ALDH1A1 (0.39) | TLR8ALDH1A1KMT2APOLBAMPD2 | |
| SCHEMBL12020590 | 0.87 | SPNS2 (0.38) | HSD11B1ALDH1A1TBXAS1TDP1LMNA | |
| SCHEMBL5283248 | 0.81 | ALDH1A1 (0.40) | TLR8ALDH1A1KMT2APOLBAMPD2 | |
| SCHEMBL5277565 | 0.81 | ALDH1A1 (0.36) | HSD11B1ALDH1A1KMT2APOLB | |
| SCHEMBL5279872 | 0.79 | ADORA2A (0.33) | HSD11B1SSTR4LMNA | |
| SCHEMBL5657308 | 0.78 | AMPD2 (0.38) | TLR8ALDH1A1KMT2APOLBAMPD1 | |
| SCHEMBL25939122 | 0.77 | ALDH1A1 (0.44) | TLR8ALDH1A1KMT2ATBXAS1POLB | |
| Hydrochloric Acid SCHEMBL5654434 | 0.76 | ALDH1A1 (0.37) | TLR8ALDH1A1KMT2APOLBAMPD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110045101-A1 | FUNGICIDAL SUBSTITUTED AZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-24 | — | — | US | disclosed |
| EP-2274284-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. Du Pont de Nemours and Company (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009137538-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009137651-A2 | FUNGICIDAL SUBSTITUTED AZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-12 | — | — | WO | disclosed |
| US-5278180-A | 4,5-bis(aryl) 4H-1,2,4-triazoles derivatives and analgesic use | ROUSSEL UCLAF (FR) | 1994-01-11 | — | — | US | disclosed |
| US-4512997-A | 4,5-Bis(aryl)-4H-1,2,4-triazole derivatives and analgesic use | ROUSSEL UCLAF (FR) | 1985-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045101-A1 | FUNGICIDAL SUBSTITUTED AZOLES | CBR3, NOX3, CBR1 | TLR8 3229/4885HSD11B1 1193/4885ALDH1A1 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.