Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941810 | 0.94 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL10831575 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL11165237 | 0.81 | LMNA (0.40) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL10939109 | 0.79 | HSP90AA1 (0.45) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL9682568 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4ELMNACYP1A2 | |
| SCHEMBL10940647 | 0.74 | HTR6 (0.33) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL11070853 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL11173454 | 0.70 | TSHR (0.46) | ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL6245883 | 0.70 | TRPA1 (0.57) | ALDH1A1KDM4ELMNACYP1A2CYP2C19 | |
| SCHEMBL51134 | 0.69 | TSHR (0.41) | ALDH1A1KMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560643-A | BLEND OF AROMATIC KETONE, POLYMER, AND GROUP IB OR EIGHT METAL SALT | CIBA GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |