Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165237 | 0.86 | LMNA (0.40) | HSP90AA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11077351 | 0.84 | HSP90AA1 (0.40) | HSP90AA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10831575 | 0.83 | SMN1; SMN2 (0.42) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL10941810 | 0.82 | ALDH1A1 (0.36) | HSP90AA1MEN1KMT2AMAPTGAA | |
| SCHEMBL10726473 | 0.82 | SRD5A2 (0.37) | HSP90AA1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11176919 | 0.82 | AKR1C3 (0.44) | HSP90AA1CTSVCTSLMEN1KMT2A | |
| SCHEMBL11164835 | 0.81 | HSP90AA1 (0.39) | HSP90AA1CTSVCTSLMEN1KMT2A | |
| SCHEMBL2695636 | 0.81 | TRPA1 (0.47) | HSP90AA1POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11177770 | 0.81 | AKR1C3 (0.38) | HSP90AA1MEN1KMT2APOLBMAPT | |
| SCHEMBL11170702 | 0.81 | HSP90AA1 (0.43) | HSP90AA1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560643-A | BLEND OF AROMATIC KETONE, POLYMER, AND GROUP IB OR EIGHT METAL SALT | CIBA GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| US-4480105-A | PHOTOCROSSLINKING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4385182-A | SENSITIZERS OR PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4363917-A | SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS | CIBA-GEIGY CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |