Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.70 |
| ▸ | HTR2C | P28335 | 10/20 | 0.70 |
| ▸ | HTR6 | P50406 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HTR5A | P47898 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 8/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832733 | 0.92 | HTR6 (0.68) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL10831691 | 0.89 | HTR6 (0.58) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL10831609 | 0.88 | HTR6 (0.57) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL10831665 | 0.87 | HTR6 (0.79) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL7646413 | 0.83 | HTR2A (1.00) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL14154501 | 0.81 | TUBB4A (0.48) | HTR2AHTR2CHTR5ADRD2MTNR1A | |
| SCHEMBL10832669 | 0.80 | HTR2A (0.64) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL10832244 | 0.78 | HTR2A (0.61) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL10832508 | 0.77 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL10831769 | 0.76 | CNR1 (0.42) | HTR2AHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544663-A | ASPERMATOGENESIS INDUCERS | SANDOZ, INC. (US) | 1985-10-01 | — | — | US | claimed |
| US-4582848-A | 2-substituted-3-indolamines and use thereof as anti-diabetics | SANDOZ, INC. (US) | 1986-04-15 | — | — | US | disclosed |
| US-4544663-A | ASPERMATOGENESIS INDUCERS | SANDOZ, INC. (US) | 1985-10-01 | — | — | US | disclosed |