Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276308 | 0.84 | HTR2A (0.57) | ALDH1A1 | |
| Iodomethane SCHEMBL7277612 | 0.83 | HTR2A (0.56) | ALDH1A1 | |
| SCHEMBL10832846 | 0.79 | KDM4E (0.50) | MTNR1AMTNR1BPDE9AALDH1A1 | |
| SCHEMBL10831591 | 0.79 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL7284370 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL2005752 | 0.77 | KDM4E (0.53) | PDE9AALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL10831701 | 0.77 | HTR2A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL10832733 | 0.75 | HTR6 (0.68) | MTNR1AMTNR1B | |
| SCHEMBL10831769 | 0.75 | CNR1 (0.42) | — | |
| SCHEMBL10925793 | 0.73 | KCNH2 (0.44) | ALDH1A1CYP1A2CYP3A4CYP2C9STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582848-A | 2-substituted-3-indolamines and use thereof as anti-diabetics | SANDOZ, INC. (US) | 1986-04-15 | — | — | US | disclosed |
| US-4544663-A | ASPERMATOGENESIS INDUCERS | SANDOZ, INC. (US) | 1985-10-01 | — | — | US | disclosed |