Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832293 | 1.00 | GPR6 (0.43) | GPR6TSHRALDH1A1TDP1MAPT | |
| SCHEMBL10832451 | 0.90 | GPR6 (0.45) | GPR6TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL10832636 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10832630 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10832468 | 0.85 | PDE4D (0.45) | ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10832466 | 0.85 | PDE4D (0.45) | ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10832702 | 0.84 | GPR6 (0.42) | GPR6TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL10832490 | 0.83 | HSD11B1 (0.40) | ALDH1A1TDP1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10832493 | 0.83 | HSD11B1 (0.40) | ALDH1A1TDP1MAPTKMT2ASMN1; SMN2 | |
| Benclonidine SCHEMBL10831623 | 0.82 | NOS1 (0.42) | GPR6ALDH1A1MAPTKMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |