Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HEXA | P06865 | 1/20 | 0.37 |
| ▸ | HEXB | P07686 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15578164 | 0.83 | NPC1 (0.40) | KMT2AALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL10269662 | 0.82 | KDM4E (0.50) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL9848741 | 0.80 | SIRT2 (0.54) | TARBP2RXRARXRBRXRGKMT2A | |
| SCHEMBL9440740 | 0.79 | SIRT2 (0.47) | TARBP2RXRARXRBRXRGHTT | |
| SCHEMBL10833341 | 0.79 | RXRA (0.37) | RXRARXRBRXRGHTTKMT2A | |
| SCHEMBL9441135 | 0.78 | RAB9A (0.52) | TARBP2HTTKMT2AALDH1A1LMNA | |
| SCHEMBL5536993 | 0.78 | ALDH1A1 (0.47) | TARBP2ALDH1A1LMNAKDM4EHTR2A | |
| SCHEMBL3914104 | 0.76 | ALDH1A1 (0.43) | TARBP2HTTKMT2AALOX12CRHR1 | |
| SCHEMBL10834263 | 0.72 | MAOA (0.44) | RXRARXRBRXRGKMT2AALDH1A1 | |
| SCHEMBL10834256 | 0.72 | RXRA (0.58) | RXRARXRBRXRGHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596816-A | Pharmaceuticals | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| EP-0092239-A2 | Oxazole derivatives, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-10-26 | — | — | EP | disclosed |