Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421386 | 0.81 | CES1 (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7348630 | 0.81 | L3MBTL1 (0.46) | HPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11595193 | 0.78 | CYP1A2 (0.49) | — | |
| SCHEMBL10008491 | 0.78 | HPGD (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL14934264 | 0.78 | PARP1 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10833177 | 0.78 | ALDH1A1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL11386026 | 0.78 | PKM (0.51) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10832727 | 0.78 | MAPT (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9037033 | 0.77 | ALDH1A1 (0.58) | KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL8440899 | 0.76 | KMT2A (0.58) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |