Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL7277612 | 0.99 | HTR2A (0.56) | HTR2AHTR2CALDH1A1CHRM3 | |
| SCHEMBL10832508 | 0.84 | MTNR1A (0.43) | ALDH1A1 | |
| SCHEMBL7284370 | 0.84 | ALDH1A1 (0.64) | ALDH1A1 | |
| SCHEMBL10832243 | 0.83 | KMT2A (0.52) | HTR2AHTR2CALDH1A1CHRM3 | |
| SCHEMBL10925793 | 0.79 | KCNH2 (0.44) | ALDH1A1CHRM3 | |
| SCHEMBL11081778 | 0.78 | CHRM3 (0.41) | HTR2CALDH1A1CHRM3 | |
| SCHEMBL11081430 | 0.76 | CHRM3 (0.40) | ALDH1A1CHRM3 | |
| SCHEMBL10832655 | 0.76 | KMT2A (0.40) | ALDH1A1CHRM3 | |
| SCHEMBL6487558 | 0.75 | KDM4E (0.63) | ALDH1A1 | |
| SCHEMBL4553629 | 0.75 | ALDH1A1 (0.72) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814344-A | ANTIEMENTICS, ANTIPSYCHOTICS | GLAXO GROUP LIMITED | 1989-03-21 | — | — | US | disclosed |
| EP-0266899-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1988-05-11 | — | — | EP | disclosed |