Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832169 | 0.92 | GPR6 (0.40) | GPR6POLBAVPR2AVPR1AMGLL | |
| Benclonidine SCHEMBL10831623 | 0.91 | NOS1 (0.42) | GPR6MGLLMAPTALDH1A1MEN1 | |
| Benclonidine SCHEMBL10831619 | 0.91 | NOS1 (0.42) | GPR6MGLLMAPTALDH1A1MEN1 | |
| SCHEMBL10832582 | 0.90 | GPR6 (0.42) | GPR6MGLLMAPTRAB9A | |
| SCHEMBL10832574 | 0.90 | HPGD (0.38) | GPR6POLBAVPR2AVPR1AMGLL | |
| SCHEMBL10832807 | 0.88 | SLC6A7 (0.39) | MAPTGAAALDH1A1SLC6A7 | |
| SCHEMBL10832370 | 0.88 | SLC6A7 (0.39) | MAPTGAAALDH1A1SLC6A7 | |
| SCHEMBL10831801 | 0.88 | GPR6 (0.42) | GPR6POLBAVPR2AVPR1AMGLL | |
| SCHEMBL10832162 | 0.88 | KCNN4 (0.44) | MGLLMAPTALDH1A1 | |
| SCHEMBL10832451 | 0.87 | GPR6 (0.45) | GPR6POLBMGLLMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |