Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benclonidine SCHEMBL10831623 | 1.00 | NOS1 (0.42) | NOS1GPR6SIGMAR1ALDH1A1HPGD | |
| SCHEMBL10832640 | 0.91 | GPR6 (0.43) | GPR6ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL10832582 | 0.89 | GPR6 (0.42) | GPR6MAPTMGLL | |
| SCHEMBL10832574 | 0.89 | HPGD (0.38) | GPR6ALDH1A1HPGDMGLL | |
| SCHEMBL10832162 | 0.89 | KCNN4 (0.44) | ALDH1A1MAPTCYP2C19MGLL | |
| SCHEMBL10832716 | 0.87 | GPR6 (0.45) | GPR6ALDH1A1HPGDHTTCYP1A2 | |
| SCHEMBL10832370 | 0.87 | SLC6A7 (0.39) | ALDH1A1MAPT | |
| SCHEMBL10832807 | 0.87 | SLC6A7 (0.39) | ALDH1A1MAPT | |
| SCHEMBL10832451 | 0.86 | GPR6 (0.45) | GPR6ALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL10832618 | 0.85 | LMNA (0.41) | GPR6MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |