Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832370 | 1.00 | SLC6A7 (0.39) | SLC6A7FFAR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10832429 | 0.89 | HCRTR1 (0.39) | SLC6A7FFAR2ALDH1A1SCN5ASCN9A | |
| SCHEMBL10832640 | 0.88 | GPR6 (0.43) | SLC6A7ALDH1A1GAAMAPT | |
| SCHEMBL10831688 | 0.88 | SLC6A7 (0.37) | SLC6A7FFAR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10833132 | 0.87 | GAA (0.38) | SLC6A7FFAR2TAS1R3TAS1R1TAS1R2 | |
| Benclonidine SCHEMBL10831623 | 0.87 | NOS1 (0.42) | ALDH1A1MAPT | |
| Benclonidine SCHEMBL10831619 | 0.87 | NOS1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL10831644 | 0.86 | SLC6A7 (0.39) | SLC6A7ALDH1A1GAAMAPTGFER | |
| SCHEMBL10832582 | 0.86 | GPR6 (0.42) | MAPT | |
| SCHEMBL10832574 | 0.86 | HPGD (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |