Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15278169 | 0.83 | PTPN1 (0.48) | PTPN1LMNATHRBKIF11ALDH1A1 | |
| SCHEMBL10832209 | 0.80 | ADORA2A (0.47) | LMNAALDH1A1NOTUMMAPK13MAPK12 | |
| SCHEMBL5544700 | 0.79 | PTGS2 (0.54) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29154647 | 0.79 | MAPK13 (0.68) | KIF11ALDH1A1MAPK13MAPK12MAPK11 | |
| SCHEMBL10832843 | 0.79 | PTPN1 (0.42) | PTPN1LMNATHRBKIF11ALDH1A1 | |
| SCHEMBL6069089 | 0.78 | PTPN1 (0.70) | PTPN1LMNATHRBNOTUM | |
| SCHEMBL6068841 | 0.77 | PTPN1 (0.73) | PTPN1LMNATHRBKIF11ALDH1A1 | |
| SCHEMBL28889445 | 0.77 | PTGS2 (0.50) | PTPN1LMNATHRBMKNK1MKNK2 | |
| SCHEMBL15578111 | 0.76 | ACHE (0.43) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5536993 | 0.76 | ALDH1A1 (0.47) | LMNAALDH1A1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596816-A | Pharmaceuticals | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| EP-0092239-A2 | Oxazole derivatives, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-10-26 | — | — | EP | disclosed |