Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68571 | 0.86 | L3MBTL1 (0.69) | HTR1ADRD2GAAL3MBTL1MAPT | |
| SCHEMBL3023243 | 0.82 | MAOB (0.51) | L3MBTL1LMNA | |
| SCHEMBL31757965 | 0.82 | CFD (0.68) | HTR1ADRD2GAAL3MBTL1MAPT | |
| SCHEMBL1007508 | 0.82 | CFD (0.68) | HTR1ADRD2GAAL3MBTL1MAPT | |
| SCHEMBL27714342 | 0.81 | HTR1A (0.65) | HTR1ADRD2GAAL3MBTL1MAPT | |
| SCHEMBL1412911 | 0.81 | HTR1A (0.59) | HTR1ADRD2GAAL3MBTL1MAPT | |
| SCHEMBL31757763 | 0.80 | L3MBTL1 (0.56) | HTR1ADRD2GAAL3MBTL1MAPT | |
| SCHEMBL2988197 | 0.80 | L3MBTL1 (0.56) | HTR1ADRD2GAAL3MBTL1MAPT | |
| SCHEMBL9026235 | 0.80 | PTPN1 (0.46) | HTR1ADRD2GAAL3MBTL1MAPT | |
| SCHEMBL7145344 | 0.80 | HTR1A (0.54) | HTR1ADRD2GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604481-A | Compounds for treatment or prophylaxis of cardiac disorders | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| US-4405642-A | BETA-BLOCKING AROMATIC ESTER COMPOUND | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |