Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850652 | 0.79 | MAPT (0.38) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL14204629 | 0.76 | LMNA (0.44) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL10297472 | 0.76 | LMNA (0.37) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL5850655 | 0.76 | ALDH1A1 (0.34) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL940949 | 0.73 | MAPT (0.45) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL1725847 | 0.73 | MAPT (0.41) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL4131351 | 0.73 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL3757859 | 0.70 | MAPT (0.42) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL1486673 | 0.70 | MAPT (0.42) | LMNASMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL272850 | 0.70 | INPPL1 (0.43) | LMNASMN1; SMN2GAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605431-A | ANTIDOTES FOR THIOLCARBAMATE HERBICIDES; PLANT SAFENING AGENTS | MONSANTO COMPANY (US) | 1986-08-12 | — | — | US | disclosed |
| US-4507143-A | REDUCE INJURY TO CROPS | MONSANTO COMPANY (US) | 1985-03-26 | — | — | US | disclosed |