SCHEMBL1725847

SCHEMBL1725847

Cc1cccc(C)c1OP(=O)(Oc1c(C)cccc1C)c1c(C)cccc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
LMNA P02545 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
SCN4A P35499 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
SCN1A P35498 2/20 0.34
SCN5A Q14524 2/20 0.34
SCN9A Q15858 2/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
KCNK3 O14649 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL940949 0.79 MAPT (0.45) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12737774 0.79 L3MBTL1 (0.55) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL14204629 0.77 LMNA (0.44) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL272850 0.76 INPPL1 (0.43) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL28397604 0.76 MAPT (0.42) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL3757859 0.76 MAPT (0.42) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL2220467 0.76 INPPL1 (0.59) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1486673 0.76 MAPT (0.42) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL4865336 0.75 ESR2 (0.40) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL4131351 0.74 SMN1; SMN2 (0.42) MAPTKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3144064-B1 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-07-28 EP disclosed
EP-3377596-A1 SELECTIVE HYDROGENATION USING A FLOW INDEX Chevron Phillips Chemical Company LP (US) 2018-09-26 EP disclosed
US-20180148260-A1 Selective Hydrogenation Using a Flow Index CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-05-31 US disclosed
US-9914676-B2 Selective hydrogenation using a flow index CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-03-13 US disclosed
US-20170349507-A1 Selective Hydrogenation Using a Flow Index CHEVRON PHILLIPS CHEMICAL COMPANY LP 2017-12-07 US disclosed
EP-3218104-A1 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2017-09-20 EP disclosed
US-9758446-B2 Selective hydrogenation using a flow index CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-09-12 US disclosed
EP-2403642-B1 METHODS OF USING A SELECTIVE HYDROGENATION CATALYST CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-08-02 EP disclosed
US-20170137346-A1 Selective Hydrogenation Using a Flow Index CHEVRON PHILLIPS CHEMICAL COMPANY LP 2017-05-18 US disclosed
EP-3144064-A2 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2017-03-22 EP disclosed
US-20160355449-A1 Hydrogenation Using Highly Selective Catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP 2016-12-08 US disclosed
WO-2016077445-A1 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2016-05-19 WO disclosed
US-20150197464-A1 Selective Hydrogenation Catalyst and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP 2015-07-16 US disclosed
US-8633127-B2 Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-01-21 US disclosed
EP-2403642-A2 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2012-01-11 EP disclosed
WO-2010101736-A2 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-09-10 WO disclosed
US-20100228065-A1 Selective Hydrogenation Catalyst and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-09-09 US disclosed