Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP7 | Q93009 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504042 | 0.75 | USP7 (0.48) | ALDH1A1USP7KDM4EMAP4K4 | |
| SCHEMBL10835414 | 0.75 | USP7 (0.50) | USP7MAP4K4 | |
| SCHEMBL31728949 | 0.71 | TGFBR1 (0.49) | IDO1ALDH1A1CNR2KDM4EMAP4K4 | |
| SCHEMBL31728766 | 0.71 | PIK3CD (0.38) | IDO1ALDH1A1CNR2SRCKDM4E | |
| SCHEMBL10961604 | 0.70 | ALDH1A1 (0.52) | IDO1ALDH1A1CNR2 | |
| SCHEMBL21223370 | 0.70 | ALDH1A1 (0.46) | IDO1ALDH1A1FGFR1SRCKDM4E | |
| SCHEMBL31729240 | 0.70 | PIK3CD (0.37) | IDO1ALDH1A1CNR2SRCKDM4E | |
| SCHEMBL11760409 | 0.70 | KMT2A (0.44) | IDO1ALDH1A1MAP4K4HAVCR2 | |
| SCHEMBL31729241 | 0.69 | IDO1 (0.36) | IDO1ALDH1A1USP7CNR2KDM4E | |
| SCHEMBL28120798 | 0.69 | FEN1 (0.52) | IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622328-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTISECRETORY AGENTS | CARPIBEM (FR) | 1986-11-11 | — | — | US | disclosed |