Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 4/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725699 | 0.81 | KMT2A (0.45) | KMT2ADHODHKMOHAVCR2ALDH1A1 | |
| SCHEMBL31728949 | 0.76 | TGFBR1 (0.49) | ALDH1A1MAP4K4IDO1 | |
| SCHEMBL11819966 | 0.74 | NAPRT (0.46) | KMOHAVCR2ALDH1A1NAPRTTYK2 | |
| SCHEMBL11821346 | 0.74 | KMO (0.51) | KMT2ADHODHKMOALDH1A1MAP4K4 | |
| SCHEMBL19138010 | 0.73 | NAPRT (0.46) | NAPRTMAP4K4 | |
| Hydrochloric Acid SCHEMBL15880101 | 0.73 | NAPRT (0.44) | KMOHAVCR2ALDH1A1NAPRTTYK2 | |
| SCHEMBL27965143 | 0.73 | KMT2A (0.51) | KMT2ADHODHALDH1A1MEN1USP2 | |
| SCHEMBL30593461 | 0.73 | KMT2A (0.51) | KMT2ADHODHHAVCR2ALDH1A1MEN1 | |
| SCHEMBL20609253 | 0.72 | DHFR (0.39) | KMT2ANAPRTLMNA | |
| SCHEMBL1260539 | 0.71 | NOS2 (0.52) | KMT2AALDH1A1NAPRTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003990-A | Anti-inflammatory polymers, pharmaceutical compositions containing the same and process for producing said polymers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-01-18 | — | — | US | disclosed |
| US-3946035-A | ADDITION POLYMERS | L'OREAL (FR) | 1976-03-23 | — | — | US | disclosed |