SCHEMBL1083606

SCHEMBL1083606

NN(C(=O)c1ccccc1)C(CCC(=O)O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPA3 P15088 1/20 0.42
NR4A2 P43354 1/20 0.42
ALDH1A1 P00352 3/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP1A2 P05177 1/20 0.40
TSHR P16473 1/20 0.40
EPOR P19235 1/20 0.39
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
GLA P06280 1/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
NFKB1 P19838 1/20 0.39
APEX1 P27695 1/20 0.39
MAPK1 P28482 1/20 0.39
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083608 1.00 CPA3 (0.42) CPA3NR4A2ALDH1A1CYP2D6CYP2C19
SCHEMBL9814706 0.89 KMT2A (0.40) ALDH1A1CYP2C19TSHRHSD17B10POLB
SCHEMBL28907590 0.88 KDM4E (0.38) CPA3CYP1A2EPORKDM4ECYP3A4
SCHEMBL11439593 0.86 KMT2A (0.46) ALDH1A1LMNAFOLH1
SCHEMBL12984206 0.81 ADRA2C (0.42) ALDH1A1CYP2C19TSHRHSD17B10KDM4E
SCHEMBL11218452 0.81 CES2 (0.41) ALDH1A1POLBHPGDMAPK1GAA
SCHEMBL9214879 0.81 CPA3 (0.41) CPA3NR4A2ALDH1A1CYP2D6CYP2C19
SCHEMBL9214861 0.81 CPA3 (0.41) CPA3NR4A2ALDH1A1CYP2D6CYP2C19
SCHEMBL4775104 0.81 CPA3 (0.42) CPA3NR4A2ALDH1A1CYP2D6CYP2C19
SCHEMBL28797503 0.81 CPA3 (0.42) CPA3NR4A2ALDH1A1CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109621860-B Stirring device, reaction tank for synthesizing folic acid and folic acid synthesizing method 河北冀衡药业股份有限公司 2024-04-12 CN claimed
CN-110627687-A Preparation method of N- (4-aminobenzoyl) -L-glutamic acid 南通雅本化学有限公司 2019-12-31 CN claimed
WO-2006096691-A9 DETERMINATION OF FOLATE IN SAMPLES OF SERUM OR PLASMA BERGEN TEKNOLOGIOVERFORING AS (NO) 2007-03-08 WO claimed
WO-2006096691-A1 DETERMINATION OF FOLATE IN SAMPLES OF SERUM OR PLASMA BERGEN TEKNOLOGIOVERFORING AS (NO) 2006-09-14 WO claimed
US-20250146046-A1 METHODS FOR DETERMINING ANTIBIOTIC SENSITIVITY RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2025-05-08 US disclosed
US-12116614-B2 Methods for determining antibiotic sensitivity RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2024-10-15 US disclosed
CN-109621860-B Stirring device, reaction tank for synthesizing folic acid and folic acid synthesizing method 河北冀衡药业股份有限公司 2024-04-12 CN disclosed
US-20230406911-A1 COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2023-12-21 US disclosed
CN-112010856-B Folic acid telescoping process method by utilizing microchannel reaction 威海中腾医药科技有限公司 2023-05-16 CN disclosed
CN-116103349-A Enzyme-catalyzed folic acid green synthesis method 苏州伯凯医药科技有限公司 2023-05-12 CN disclosed
CN-112858511-B Method for detecting N- (4-aminobenzoyl) -L-glutamic acid in vitamin freeze-dried powder injection 费森尤斯卡比华瑞制药有限公司 2023-05-02 CN disclosed
CN-112858511-B Method for detecting N- (4-aminobenzoyl) -L-glutamic acid in vitamin freeze-dried powder injection 费森尤斯卡比华瑞制药有限公司 2023-05-02 CN disclosed
EP-0813510-A4 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 2000-07-26 EP disclosed
US-5846908-A Methods and compositions for enhancing plant growth with p-amino- or p-nitro-benzoic acids NONOMURA ARTHUR M (US) 1998-12-08 US disclosed
EP-0813510-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA, Arthur M. (US) 1997-12-29 EP disclosed
CN-1162643-A Preparation and usage of molecular chimera for curing cancer WELLCOME FOUND (GB) 1997-10-22 CN disclosed
WO-1996027572-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 1996-09-12 WO disclosed
EP-0319598-B1 STABILIZED AQUEOUS PREPARATION OF FOLIC ACID Blum, Holger (DE) 1991-09-25 EP disclosed
CN-1050899-A NOVEL ENTITIES FOR CANCER THERAPY WELLCOME FOR CANCER THERAPY (GB) 1991-04-24 CN disclosed
US-4931442-A Stabilized aqueous folic acid preparation BLUM HOLGER (DE) 1990-06-05 US disclosed