Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 9/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | OGT | O15294 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837291 | 0.95 | DRD2 (0.57) | ALDH1A1ATMGRIN2BDRD2HTR1A | |
| SCHEMBL10835956 | 0.90 | KCNH2 (0.50) | ALDH1A1ATMGRIN2BDRD2HTR1A | |
| SCHEMBL10837913 | 0.85 | DRD2 (0.53) | DRD2HTR1AHTR2AKCNH2DRD4 | |
| SCHEMBL10836115 | 0.85 | KCNH2 (0.66) | GRIN2BDRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL10835827 | 0.85 | DRD2 (0.51) | ALDH1A1ATMGRIN2BDRD2HTR1A | |
| SCHEMBL10835876 | 0.85 | GRIN2B (0.54) | GRIN2BDRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL8549343 | 0.84 | GRIN2B (0.59) | GRIN2BMEN1KMT2AOGT | |
| SCHEMBL10837721 | 0.83 | HTR1A (0.65) | DRD2HTR1AALOX15DRD4DRD3 | |
| SCHEMBL10837209 | 0.82 | DRD2 (0.57) | ALDH1A1GRIN2BDRD2HTR1AHTR2A | |
| SCHEMBL10838656 | 0.82 | GRIN2B (0.51) | GRIN2BDRD2HTR1AHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619932-A | CENTRAL NERVOUS SYSTEM CONTROLLERS; ANTI-SCHIZOPHRENIA AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4605431-A | ANTIDOTES FOR THIOLCARBAMATE HERBICIDES; PLANT SAFENING AGENTS | MONSANTO COMPANY (US) | 1986-08-12 | — | — | US | disclosed |
| US-4567187-A | CENTRAL NERVOUS SYSTEM | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4460593-A | Carbostyril derivatives, and central nervous system controlling agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4455422-A | ANTIHISTAMINES, CNS CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-19 | — | — | US | disclosed |