Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165353 | 0.89 | HTR1A (0.58) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL4851475 | 0.88 | HTR1A (0.57) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL5467252 | 0.86 | HTR1A (0.52) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL4859545 | 0.83 | HDAC3 (0.57) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10838818 | 0.82 | HTR1A (0.56) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10461840 | 0.81 | HTR7 (0.55) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL8546755 | 0.81 | AKR1C4 (0.49) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL1145012 | 0.81 | ALDH1A1 (0.55) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10463736 | 0.80 | HTR1A (0.54) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10495760 | 0.80 | CRBN (0.47) | HTR1AHTR2AHTR7DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4626532-A | Process for stabilization of bacampicillin hydrochloride | ASTRA LAKEMEDEL AKTIEBOAG (SE) | 1986-12-02 | — | — | US | disclosed |
| US-4619932-A | CENTRAL NERVOUS SYSTEM CONTROLLERS; ANTI-SCHIZOPHRENIA AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4567187-A | CENTRAL NERVOUS SYSTEM | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4460593-A | Carbostyril derivatives, and central nervous system controlling agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4455422-A | ANTIHISTAMINES, CNS CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-19 | — | — | US | disclosed |