Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838225 | 0.98 | FAAH (0.50) | FAAHCA2CES1CES2 | |
| SCHEMBL11008369 | 0.92 | NPC1 (0.41) | FAAHCA2CES1NPC1S1PR2 | |
| SCHEMBL10836656 | 0.81 | — | — | |
| SCHEMBL10838853 | 0.78 | — | — | |
| SCHEMBL11133468 | 0.77 | CA2 (0.48) | FAAHCA2TP53 | |
| SCHEMBL3999902 | 0.77 | FAAH (0.48) | FAAHCA2CES1NPC1S1PR2 | |
| SCHEMBL28587125 | 0.77 | FAAH (0.48) | FAAHCA2CES1NPC1S1PR2 | |
| SCHEMBL17109068 | 0.75 | FAAH (0.52) | FAAHCA2CES1CES2 | |
| SCHEMBL14892312 | 0.75 | FAAH (0.52) | FAAHCA2CES1CES2 | |
| SCHEMBL19776015 | 0.75 | FAAH (0.52) | FAAHCA2CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4591618-A | HIGH STRENGTH BONDING AGENTS | BRIDGESTONE TIRE CO., LTD. (JP) | 1986-05-27 | — | — | US | disclosed |
| US-4535003-A | WITH HALOGEN RELEASING HALOGENOID, WAX AND FILLER | BRIDGESTONE TIRE CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |
| US-4500685-A | MIXTURES OF HALOSULFONAMIDE AND WAX | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4117036-A | ANAEROBIC CURABILITY, SEALANTS | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1978-09-26 | — | — | US | disclosed |