Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 7/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838527 | 1.00 | STS (0.52) | STSEGFRERBB2GAACA1 | |
| SCHEMBL10837093 | 0.86 | ALDH1A1 (0.46) | STSGAACA1CA2LMNA | |
| SCHEMBL10837099 | 0.86 | ALDH1A1 (0.46) | STSGAACA1CA2LMNA | |
| SCHEMBL10838725 | 0.84 | POLB (0.43) | GAACYP3A4POLB | |
| SCHEMBL10838737 | 0.84 | POLB (0.43) | GAACYP3A4POLB | |
| SCHEMBL10838937 | 0.82 | POLB (0.43) | GAACA1CA2CA12CA9 | |
| SCHEMBL10838952 | 0.82 | POLB (0.43) | GAACA1CA2CA12CA9 | |
| SCHEMBL5931119 | 0.77 | EGFR (0.74) | EGFRERBB2GAALMNACA12 | |
| SCHEMBL10547616 | 0.75 | GAPDH (0.40) | PKM | |
| SCHEMBL10413872 | 0.75 | MAPK1 (0.38) | LMNACYP3A4L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062876-B1 | 2-OXO-1-(((SUBSTITUTED SULFONYL)AMINO)CARBONYL)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4587047-A | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0062876-A1 | 2-Oxo-1-(((substituted sulfonyl)amino)carbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1982-10-20 | — | — | EP | disclosed |