Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | KCNA1 | Q09470 | 2/20 | 0.43 |
| ▸ | KCNAB1 | Q14722 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838680 | 1.00 | LMNA (0.48) | LMNAALDH1A1AKR1C3POLBNFKB1 | |
| SCHEMBL10838560 | 0.88 | DHFR (0.49) | LMNAALDH1A1CYP3A4CA1CA2 | |
| SCHEMBL10838552 | 0.88 | DHFR (0.49) | LMNAALDH1A1CYP3A4CA1CA2 | |
| SCHEMBL10837099 | 0.82 | ALDH1A1 (0.46) | LMNAALDH1A1AKR1C3POLBNFKB1 | |
| SCHEMBL10837093 | 0.82 | ALDH1A1 (0.46) | LMNAALDH1A1AKR1C3POLBNFKB1 | |
| SCHEMBL10837389 | 0.75 | — | — | |
| SCHEMBL10838533 | 0.74 | STS (0.52) | LMNAPOLBCYP3A4GAACA1 | |
| SCHEMBL10838527 | 0.74 | STS (0.52) | LMNAPOLBCYP3A4GAACA1 | |
| SCHEMBL10839312 | 0.74 | — | — | |
| SCHEMBL10838689 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062876-B1 | 2-OXO-1-(((SUBSTITUTED SULFONYL)AMINO)CARBONYL)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1986-09-24 | — | — | EP | claimed |
| US-4587047-A | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1986-05-06 | — | — | US | claimed |
| EP-0062876-A1 | 2-Oxo-1-(((substituted sulfonyl)amino)carbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1982-10-20 | — | — | EP | claimed |