Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 9/20 | 0.37 |
| ▸ | NOS2 | P35228 | 9/20 | 0.37 |
| ▸ | NOS3 | P29474 | 4/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | LSS | P48449 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838678 | 0.95 | NOS1 (0.40) | NOS1NOS2NOS3SCN2ACHRNB2 | |
| SCHEMBL8985640 | 0.70 | ALPL (0.41) | NOS1NOS2NOS3SCN2A | |
| SCHEMBL10839535 | 0.67 | NOS1 (0.37) | NOS1NOS2NOS3CHRNB2CHRNA7 | |
| SCHEMBL6469065 | 0.62 | ALDH1A1 (0.36) | NOS1NOS2NOS3SCN2AALOX5 | |
| SCHEMBL11648945 | 0.62 | NOS1 (0.37) | NOS1NOS2NOS3SCN2AGRM2 | |
| Hydrochloric Acid SCHEMBL3668932 | 0.61 | GBA1 (0.41) | NOS1NOS2NOS3SCN2A | |
| SCHEMBL21122272 | 0.60 | INMT (0.43) | NOS1NOS2NOS3 | |
| SCHEMBL9400270 | 0.59 | NOS1 (0.44) | NOS1NOS2NOS3SCN2A | |
| SCHEMBL16566350 | 0.59 | GBA1 (0.39) | NOS1NOS2NOS3SCN2A | |
| SCHEMBL21229670 | 0.59 | INMT (0.41) | NOS1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4603206-A | ALCOHOLS, ETHERS FROM MERCAPTANS, SULFIDES;POSITIVE HALOGENATING AGENT; ALCOHOL; IMMUNOMODULATORS | PENNWALT CORPORATION (US) | 1986-07-29 | — | — | US | disclosed |
| US-4560758-A | IMMUNOMODULATORS | PENNWALT CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| US-4551535-A | SULFIDING IN THE PRESENCE OF A BASE | PENNWALT CORPORATION (US) | 1985-11-05 | — | — | US | disclosed |
| EP-0150255-A2 | Pyrrolo[1,2-a]imidazole and imidazo[1,2-a]pyridine immunomodulators | FISONS CORPORATION (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4507481-A | IMMUNOMODULATORS | PENNWALT CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |