Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840693 | 0.80 | LMNA (0.34) | PDE3BPDE3ACYP3A4TSHRMEN1 | |
| SCHEMBL10840013 | 0.77 | HTR2C (0.40) | TSHRMEN1LMNAKMT2AGABRP | |
| SCHEMBL11087883 | 0.74 | PDE3B (0.45) | DRD2DRD3PDE3BPDE3ALMNA | |
| SCHEMBL24347621 | 0.73 | DRD2 (0.40) | DRD2DRD3PDE3BPDE3AEGFR | |
| SCHEMBL10839817 | 0.73 | PNMT (0.39) | MEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL8258749 | 0.73 | PDE3B (0.44) | DRD2DRD3PDE3BPDE3AEGFR | |
| SCHEMBL5208272 | 0.73 | TSHR (0.49) | TSHRLMNA | |
| SCHEMBL5213527 | 0.73 | TSHR (0.49) | TSHRLMNA | |
| SCHEMBL5208279 | 0.73 | TSHR (0.49) | TSHRLMNA | |
| SCHEMBL7362916 | 0.72 | SLC22A1 (0.52) | DRD2DRD3SLC22A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |