Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840683 | 0.84 | HTR2A (0.37) | ARHTR2AHTR2CPDE7ASRD5A1 | |
| SCHEMBL10839029 | 0.82 | KDM4E (0.32) | ARPGR | |
| SCHEMBL10841314 | 0.79 | CES1 (0.38) | ARHTR2AHTR2CPDE7ASRD5A1 | |
| SCHEMBL10839480 | 0.75 | HTR5A (0.41) | ARPDE7AAKT1 | |
| SCHEMBL10841141 | 0.74 | AHR (0.43) | ARHTR2AHTR2CPDE7A | |
| SCHEMBL6648593 | 0.74 | AR (0.33) | AR | |
| SCHEMBL10840084 | 0.72 | AKT1 (0.41) | ARHTR2AHTR2CNR3C1PGR | |
| SCHEMBL22958360 | 0.70 | CYP11B1 (0.40) | HTR2ASRD5A1 | |
| SCHEMBL10840092 | 0.69 | PDE7A (0.40) | ARPGRPDE7AAKT1 | |
| SCHEMBL10911499 | 0.68 | KDM4E (0.39) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |