Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MECP2 | P51608 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843630 | 0.90 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL10842419 | 0.85 | KDM4E (0.36) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL10842915 | 0.81 | CHEK1 (0.45) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL10842100 | 0.81 | NPC1 (0.37) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL10840481 | 0.78 | KDM4E (0.52) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL10841737 | 0.74 | THRB (0.61) | ALDH1A1HPGDMEN1KMT2AMAP4K4 | |
| SCHEMBL5470112 | 0.71 | CHEK1 (0.61) | — | |
| SCHEMBL10842650 | 0.69 | NPSR1 (0.53) | ALDH1A1HPGDMEN1KMT2ARECQL | |
| SCHEMBL16431919 | 0.65 | MAP4K4 (0.56) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL21539290 | 0.64 | MAP4K4 (0.51) | ALDH1A1HPGDHSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |