Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843797 | 0.90 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL10842419 | 0.89 | KDM4E (0.36) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL10840481 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL10842915 | 0.84 | CHEK1 (0.45) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL10842100 | 0.84 | NPC1 (0.37) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL10842650 | 0.78 | NPSR1 (0.53) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL10841737 | 0.69 | THRB (0.61) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL10842636 | 0.69 | POLB (0.51) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL10841715 | 0.68 | THRB (0.45) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL11779422 | 0.66 | KDM4E (0.61) | ALDH1A1KDM4EKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |