Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841208 | 0.81 | ALDH1A1 (0.47) | PGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10840158 | 0.76 | CES1 (0.42) | PGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10840374 | 0.73 | NSD2 (0.42) | PGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL5504578 | 0.71 | CES1 (0.46) | PGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10840555 | 0.67 | ALDH1A1 (0.67) | PGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6650129 | 0.66 | ALDH1A1 (0.46) | PGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4193038 | 0.64 | CES1 (0.46) | PGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10840255 | 0.63 | PGR (0.30) | PGRAR | |
| SCHEMBL10840367 | 0.62 | KDM4E (0.47) | PGRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10840500 | 0.61 | ALDH1A1 (0.53) | PGRALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |