Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509713 | 0.92 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL10838768 | 0.91 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL10837909 | 0.89 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL10839794 | 0.88 | ADRA1A (0.45) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL10840999 | 0.85 | HTR1A (0.52) | ADRA1DADRA1AADRA1BDRD3HTR1A | |
| SCHEMBL10839824 | 0.81 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL10839624 | 0.78 | DRD2 (0.54) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL10506821 | 0.77 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL10511914 | 0.76 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL10509662 | 0.76 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BDRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4629728-A | ANTIISCHEMIC AND -METABOLIC AGENTS | ADIR S.A.R.L. (FR) | 1986-12-16 | — | — | US | disclosed |