Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10842066 | 0.87 | LMNA (0.48) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL10841396 | 0.87 | LMNA (0.50) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL10842250 | 0.87 | LMNA (0.50) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL8876726 | 0.86 | LMNA (0.53) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL8875692 | 0.86 | LMNA (0.47) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL10839612 | 0.85 | ALOX5 (0.55) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL10841390 | 0.84 | LMNA (0.51) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL10842711 | 0.83 | ALDH1A1 (0.57) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL2480956 | 0.83 | LMNA (0.63) | LMNAMAPTSMN1; SMN2NPSR1GAA | |
| SCHEMBL10841738 | 0.82 | LMNA (0.54) | LMNAMAPTSMN1; SMN2NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594345-A | Containing a 2-phenyl substituted chroman-4-one ring | NIPPON SHINYAKU CO. LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0100250-A2 | Methylflavone derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-02-08 | — | — | EP | disclosed |