Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 10/20 | 0.36 |
| ▸ | HTR2A | P28223 | 9/20 | 0.36 |
| ▸ | HTR2B | P41595 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840190 | 0.82 | MEN1 (0.50) | CREBBPHTR2CHTR2AHTR2BKDM4E | |
| SCHEMBL19511078 | 0.81 | ALDH1A1 (0.35) | CREBBPKDM4EMEN1ALOX15KMT2A | |
| SCHEMBL10841259 | 0.79 | MEN1 (0.33) | KDM4EMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL10838799 | 0.79 | AR (0.34) | BRD4CREBBPHTR2CHTR2AHTR2B | |
| SCHEMBL10841078 | 0.77 | HTR2C (0.41) | BRD4CREBBPHTR2CHTR2BMEN1 | |
| Hydrochloric Acid SCHEMBL11332118 | 0.73 | HTR2C (0.39) | HTR2CHTR2AHTR2B | |
| SCHEMBL10840679 | 0.71 | MEN1 (0.50) | CREBBPHTR2CHTR2AHTR2BKDM4E | |
| SCHEMBL19511452 | 0.69 | SRC (0.35) | — | |
| SCHEMBL19056900 | 0.69 | CCR1 (0.42) | HTR2CHTR2AHTR2BKCNH2 | |
| SCHEMBL9510659 | 0.68 | PNMT (0.42) | HTR2CHTR2AHTR2BKCNH2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |