Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840679 | 0.80 | MEN1 (0.50) | HTR2CHTR5AADRA2AADRA2BADRA2C | |
| SCHEMBL30163317 | 0.80 | MEN1 (0.50) | HTR2CHTR5AADRA2AADRA2BADRA2C | |
| SCHEMBL9394752 | 0.79 | CD44 (0.36) | CREBBPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10841161 | 0.79 | ALDH1A1 (0.39) | HTR5ABRD4CREBBPHTR1AHTR7 | |
| SCHEMBL3950953 | 0.79 | CHRM3 (0.41) | HTR2CHTR2BHTR1A | |
| SCHEMBL19511078 | 0.78 | ALDH1A1 (0.35) | CREBBPALDH1A1MEN1KMT2AGFER | |
| SCHEMBL10841335 | 0.78 | AHR (0.37) | HTR2CAHRHTR5AADRA2AADRA2B | |
| SCHEMBL10840724 | 0.77 | BRD4 (0.39) | HTR2CBRD4CREBBPHTR2BMEN1 | |
| SCHEMBL18602431 | 0.76 | HTR1A (0.40) | CREBBPHTR1AALDH1A1MEN1KMT2A | |
| SCHEMBL10840744 | 0.76 | PDK2 (0.39) | HTR2CCREBBPHTR2BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |