Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.36 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 7/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841161 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL10840679 | 0.76 | MEN1 (0.50) | MEN1KMT2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL30163317 | 0.76 | MEN1 (0.50) | MEN1KMT2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL9394752 | 0.75 | CD44 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3950953 | 0.75 | CHRM3 (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL10841078 | 0.75 | HTR2C (0.41) | PNMTMEN1KMT2AHTR2CHTR2B | |
| SCHEMBL19511078 | 0.74 | ALDH1A1 (0.35) | ARMEN1KMT2AALDH1A1 | |
| SCHEMBL10840744 | 0.72 | PDK2 (0.39) | MEN1KMT2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL18602431 | 0.72 | HTR1A (0.40) | ARMEN1KMT2AALDH1A1 | |
| SCHEMBL11422593 | 0.72 | DRD2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |