Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | F2RL3 | Q96RI0 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10842673 | 0.93 | MAPT (0.45) | L3MBTL1F2RL3MAPTMEN1KMT2A | |
| SCHEMBL10840819 | 0.80 | ADORA2A (0.47) | SMN1; SMN2HPGD | |
| SCHEMBL11706515 | 0.75 | L3MBTL1 (0.57) | L3MBTL1F2RL3MAPTMEN1KMT2A | |
| SCHEMBL19036232 | 0.73 | HRH4 (0.54) | MAPTLMNAHRH4HRH3HPGD | |
| SCHEMBL23576822 | 0.69 | ABCG2 (0.47) | L3MBTL1F2RL3MAPTMEN1KMT2A | |
| SCHEMBL30960991 | 0.69 | ABCG2 (0.47) | L3MBTL1F2RL3MAPTMEN1KMT2A | |
| SCHEMBL13576578 | 0.69 | MAPT (0.65) | L3MBTL1F2RL3MAPTMEN1KMT2A | |
| SCHEMBL2420647 | 0.68 | MAPT (0.64) | L3MBTL1F2RL3MAPTMEN1KMT2A | |
| SCHEMBL9038869 | 0.66 | POLB (0.58) | MEN1KMT2AHRH4HRH3 | |
| SCHEMBL10842650 | 0.66 | NPSR1 (0.53) | L3MBTL1F2RL3MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |