Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841737 | 0.92 | THRB (0.61) | NPSR1THRBTDP1RECQLL3MBTL1 | |
| SCHEMBL10841715 | 0.90 | THRB (0.45) | NPSR1THRBTDP1RECQLL3MBTL1 | |
| SCHEMBL10842636 | 0.86 | POLB (0.51) | NPSR1THRBTDP1RECQLPOLB | |
| SCHEMBL10842811 | 0.86 | NPBWR1 (0.42) | NPSR1THRBTDP1RECQLL3MBTL1 | |
| SCHEMBL10842466 | 0.86 | MEN1 (0.47) | NPSR1THRBTDP1RECQLMAPT | |
| SCHEMBL11849955 | 0.80 | L3MBTL1 (0.50) | NPSR1THRBTDP1RECQLL3MBTL1 | |
| SCHEMBL11702410 | 0.71 | L3MBTL1 (0.58) | NPSR1THRBL3MBTL1POLBMAPT | |
| SCHEMBL11819978 | 0.70 | MAPT (0.41) | NPSR1THRBTDP1RECQLL3MBTL1 | |
| SCHEMBL10843797 | 0.69 | ALDH1A1 (0.40) | NPSR1THRBTDP1RECQLPOLB | |
| SCHEMBL10840481 | 0.69 | KDM4E (0.52) | THRBL3MBTL1POLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |